Huizhou Pengchengrui Technology Co., Ltd.

Main materials of medical intervention guide wire

A guide wire is generally divided into three parts: core wire (inner core), developing winding/sheath, and surface coating

1. Core wire (the main body that bears thrust and torque)

-Nickel titanium alloy (Nitinol): the most commonly used nowadays, with super elasticity and shape memory, not easy to bend or twist, soft tip, and is mostly used for blood vessels, urinary tract loach guide wires, and zebra guide wires

-Medical stainless steel (304V/316LVM): good rigidity, strong torque transmission, commonly used in traditional coronary artery guide wires and hard guide wires; Not as flexible as nickel titanium, easily twisted and bent

>There are also hybrid cores: the proximal stainless steel provides support, and the distal nickel titanium ensures softness (common for coronary micro guide wires)

Nickel titanium alloy guide wire

2. Head end development/coating structure (visible under X-ray)

-Platinum tungsten alloy, platinum iridium alloy: spiral wound wire at the tip, high X-ray opacity, clear view of the guide wire tip under fluoroscopy, essential for vascular intervention micro guide wire

-Polymer sheath: polyurethane TPU (often mixed with tungsten powder to increase development), PTFE (PTFE), wrapped around the core wire to protect the inner core and reduce friction; Zebra guide wire is PTFE with striped sheath

3. Surface coating (for lubrication)

-Hydrophilic coating: PVP (polyvinylpyrrolidone), which forms hydrogel when encountering water, with extremely low friction. The distal end of loach guide wire and most vascular micro guide wires are PVP hydrophilic coating

-Hydrophobic coating: PTFE (polytetrafluoroethylene/Teflon), smooth and friction resistant, commonly used in the proximal part of guide wires

Simply distinguish several common guide

-Mud loach guide wires wire: nickel titanium core+TPU sheath+PVP hydrophilic coating

-Zebra guide wire: nickel titanium core+black and white striped PTFE sheath

-Traditional coronary coil guide wire: stainless steel core+platinum tungsten spring winding+PTFE coating

>All materials require implant grade biocompatibility, corrosion resistance, and one-time sterile use.

Pengchengrui Technology in Huizhou City is a professional manufacturer of medical intervention guide wires, providing products such as super elastic guide wires, taper grinding wires, medical guide wire accessory cores, and micro guide wires. Supports processing of fine wire materials ranging from 0.03mm to 1.0mm, with a maximum grinding length of 600mm and high dimensional accuracy. Relying on mature precision grinding technology, the surface of the wire material is smooth, elastic and stable, meeting the strict requirements of blood vessels and minimally invasive interventional instruments. It can undertake various non-standard customizations and assist in the research and mass production of medical devices.